Meropenem (Sterile) I.P.
eq. to Meropenem…...1000 mg.
(A mixture of sterile Meropenem and sodium Carbonate IP)
eq. to Sodium…….90.2 mg (as buffer)
1 FFS Ampoule of sterile water for Injection I.P. 20 ml.
Reconstitution :
- Meropenem to be used for bolus intravenous injection should be reconstituted with sterile water for injection.
- For intravenous infusion, meropenem vials may be directly reconstituted with 0.9 % sodium chloride or 5% glucose solutions for infusion. Each vial is for single use only.
Storage :
- Store between 15 - 30°C. Do not freeze.
Disease |
Adults |
Pediatric |
Complicated Skin/Skin Structure Infections (cSSI)
|
500 mg IV q8hr; not to exceed 2 g IV q8hr |
≥3 months: 10 mg/kg IV q8hr; not to exceed 500 mg IV q8hr |
Complicated Intra-abdominal Infections |
1 g IV q8hr; not to exceed 2 g IV q8hr |
≥3 months: 20 mg/kg IV q8hr; not to exceed 1 g q8hr
|
Community-Acquired Pneumonia |
500 mg IV q8hr for ≤5 days in combination with fluoroquinolone. |
|
Febrile Neutropenia |
1 g IV q8hr
|
|
Bacterial Meningitis
|
40mg/kg to 2gm Maximum
Every 8 Hrs.
|
≥3 months: 40 mg/kg IV q8hr; not to exceed 2 g IV q8hr
|
Route of Administration:
IV/IM